NK cells are intrinsically functional in pigs with Severe Combined Immunodeficiency (SCID) caused by spontaneous mutations in the Artemis gene

Human severe combined immunodeficiency: Genetic, phenotypic, and functional diversity in one hundred eight infants

Rebecca H. Buckley, Richard I. Schiff, Sherrie E. Schiff et al. · The Journal of Pediatrics · 1997 · 548 citations

Life Sciences, Immunology, Pediatrics +14

Acquisition of Murine NK Cell Cytotoxicity Requires the Translation of a Pre-existing Pool of Granzyme B and Perforin mRNAs

Todd A. Fehniger, Sheng F. Cai, Xuefang Cao et al. · Immunity · 2007 · 452 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Structural and functional annotation of the porcine immunome

Harry Dawson, Jane Loveland, Géraldine Pascal et al. · BMC Genomics · 2013 · 209 citations · Full text

Life Sciences, Bioinformatics, Immunology +15

SCID patients with ARTEMIS vs RAG deficiencies following HCT: increased risk of late toxicity in ARTEMIS-deficient SCID

Catharina Schuetz, Bénédicte Neven, Christopher C. Dvorak et al. · Blood · 2013 · 173 citations · Full text

Medicine, Immunology, Toxicology +9

Perforin expression can define CD8 positive lymphocyte subsets in pigs allowing phenotypic and functional analysis of Natural Killer, Cytotoxic T, Natural Killer T and MHC un-restricted cytotoxic T-cells

M. Denyer, Thomas Wileman, Catrina Stirling et al. · Veterinary Immunology and Immunopathology · 2005 · 123 citations

Life Sciences, Immunology, Cellular Immunology +15