New England Journal of Medicine · 1968 · 157 citations · 6 references
MedicineNeurosurgeryOncologyChemotherapyNeuro-oncologySolid Tumor PharmacotherapyBrain TumorsDrainage ProceduresIntrathecal ChemotherapyCerebrospinal Fluid CollectionCerebrospinal Fluid SamplingComplication Rate AnalysisIntrathecal Chemotherapy AdministrationNeurosurgical DrainageSubcutaneous Fluid Therapy
A subcutaneous cerebrospinal-fluid reservoir was used in 60 patients between 1962 and 1968. The total complication rate related to the reservoirs was 28 per cent. Major complications numbered six. Surgical revision, usually within the first three months after installation, was necessary in 25 per cent. After the first three months, complications were less frequent. The reservoirs were used for the chemotherapy of neoplasia, cystic tumor drainage, ventricular drainage, special diagnostic studies and the sampling of cerebrospinal fluid. The reservoirs were particularly useful for intrathecal chemotherapy of resistant meningeal leukemia with perfusion technics, and for drainage of intracranial cysts. In selected cases, the advantages of the subcutaneous reservoir outweigh the morbidity incurred.
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Subarachnoid Distribution of Drugs after Lumbar Injection
Richard E. Rieselbach, Giovanni Di Chiro, Emil J. Freireich et al. · New England Journal of Medicine · 1962 · 215 citations
Cerebrospinal fluid perfusion for central nervous system neoplasms
Robert C. Rubin, Ayub K. Ommaya, Edward S. Henderson et al. · Neurology · 1966 · 98 citations
Medicine, Neuroscience, Neurosurgery +13