Concepedia

NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses

Haitao Guo, Renate König, Meng Deng, Jinyao Mo, Lu Zhang, Alex Petrucelli, Sunnie M. Yoh, Brice E. Barefoot, M. U. Samo, Gregory D. Sempowski,

Cell Host & Microbe · 2016 · 148 citations · 38 references

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38

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

, , +12

Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Jiaxi Wu, Lijun Sun, Xiang Chen et al. · Science · 2012 · 2.5K citations

, , +17

IFI16 is an innate immune sensor for intracellular DNA

Leonie Unterholzner, Sinéad E. Keating, Marcin Baran et al. · Nature Immunology · 2010 · 1.6K citations · Full text

, , +14

STING is a direct innate immune sensor of cyclic di-GMP

Dara Burdette, Kathryn M. Monroe, Katia Troha et al. · Nature · 2011 · 1.5K citations

, , +12