Choleretic Action of Cortisone

Abstract

ACTH and cortisone have had extensive therapeutic trials in the management of acute and chronic diseases of the liver. Most patients with acute hepatitis treated with ACTH or cortisone, as reported by Colbert et al.,1 Sborov and his colleagues2 and Evans, Sprinz and Nelson,3 showed prompt improvements in appetite and sense of well-being, accompanied by sharp decreases in serum bilirubin levels, which fell to normal in a shorter period than those of untreated groups.2 Clinical remission was significantly hastened. However, the frequency and severity of complications that occurred during administration and the relapses after withdrawal limit the usefulness of these . . .