Concepedia

ZEB1 expression is associated with prognosis of intrahepatic cholangiocarcinoma

Katsumi Terashita, Makoto Chuma, Yutaka Hatanaka, Kanako C. Hatanaka, Tomoko Mitsuhashi, Hideki Yokoo, Takumi Ohmura, Hiroyuki Ishizu, Shunji Muraoka, Atsushi Nagasaka,

Journal of Clinical Pathology · 2015 · 18 citations · 21 references

DOI

Abstract

ZEB1 expression is associated with tumour progression and poor prognosis in patients with ICC through positive correlations with vimentin and negative correlations with E-cadherin. ZEB1 expression is associated with a poor prognosis and might be an attractive target for the treatment of ICC.

References

21

Global cancer statistics

Ahmedin Jemal, Freddie Bray · CA A Cancer Journal for Clinicians · 2011 · 55K citations · Full text

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

Ulrich F. Wellner, Jörg Schubert, Ulrike Burk et al. · Nature Cell Biology · 2009 · 1.7K citations

, , +5

Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

Naoki Oishi, Mia R. Kumar, Stéphanie Roessler et al. · Hepatology · 2012 · 279 citations · Full text

Prognostic Factors After Surgical Resection for Intrahepatic, Hilar, and Distal Cholangiocarcinoma

Yoshiaki Murakami, Kenichiro Uemura, Takeshi Sudo et al. · Annals of Surgical Oncology · 2010 · 236 citations

, , +11

Claudin-1 Up-regulates the Repressor ZEB-1 to Inhibit E-Cadherin Expression in Colon Cancer Cells

Amar B. Singh, Ashok Sharma, J. Joshua Smith et al. · Gastroenterology · 2011 · 165 citations · Full text

, , +10