Case 38-2007

Abstract

A 44-year-old woman was admitted to this hospital because of generalized, painful, ulcerated skin lesions. Four years before admission, she had generalized hyperkeratotic lesions that responded poorly to treatment. Biopsy specimens had been interpreted as squamous-cell carcinoma. Three months before admission, mycophenolate mofetil was begun; some of the lesions regressed, but 1 month later, new painful nodules and plaques developed, with central necrosis and ulceration.