Publication | Closed Access
Codes for DNA Sequence Profiles
113
Citations
30
References
2016
Year
EngineeringGeneticsDna AnalysisMolecular BiologyGenomicsSequence DesignDna Sequence ProfilesMolecular EcologyDna ComputingDna SequencingSynthetic Dna MediaSequence AnalysisDna Storage ChannelDna ReplicationNew Channel ModelFunctional GenomicsBioinformaticsComputational BiologyGenetic EngineeringSynthetic BiologyMedicineGenome EditingSequence Assembly
We consider the problem of storing and retrieving information from synthetic DNA media. We introduce the DNA storage channel and model the read process through the use of profile vectors. We provide an asymptotic analysis of the number of profile vectors and propose new asymmetric coding techniques to combat the effects of synthesis and sequencing noise. Furthermore, we construct two families of codes for this new channel model.
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