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Isolation and structure elucidation of teleocidin B-1, B-2, B-3, and B-4.
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1984
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Combinatorial ChemistryBioorganic ChemistryMolecular BiologySecondary MetaboliteChemical BiologyPharmaceutical ChemistryStructure ElucidationNatural Product BiosynthesisBiochemistryTeleocidin B-1MetabolomicsNatural Product SynthesisPrimary MetaboliteCrystalline StatesTeleocidin BOlivoretin DNatural SciencesMicrobiologyMedicineDrug Discovery
From the mycelia of Streptomyces mediocidicus four metabolites teleocidin B-1, B-2, B-3 and B-4 were isolated in crystalline states and their structures were determined by comparison with the known des-O-methylolivoretin B, and olivoretin D (teleocidin B of Hirata), and by studying the 13C-nuclear magnetic resonance (NMR) spectra.