FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination.

Nobuharu Shigematsu, Hirotsugu Ueda, Shigehiro Takase, Hirokazu Tanaka, Kyoko Yamamoto, TOSHUIJI TADA

The Journal of Antibiotics · 1994 · 131 citations · 4 references

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Abstract

The structure of FR901228 (C24H36N4O6S2), including stereochemical details, was determined by a combination of spectroscopic, chemical evidence and single-crystal X-ray crystallographic analysis using anomalous dispersion from the S atoms.

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