Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

Jiping Zha, Hisashi Harada, Elizabeth Yang et al. · Cell · 1996 · 2.6K citations · Full text

Life Sciences, Cell Biology, Apoptosis +15

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

Jay P. Morgenstern, Hartmut Land · Nucleic Acids Research · 1990 · 2.1K citations · Full text

Pharmacy, Pharmaceutics, Gene Delivery +15

Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death

Elizabeth Yang, Jiping Zha, Jennifer Jockel et al. · Cell · 1995 · 2.1K citations · Full text

Life Sciences, Cancer Biology, Cell Biology +7

Improved retroviral vectors for gene transfer and expression.

A. Dusty Miller, G J Rosman · PubMed · 1989 · 2K citations

Life Sciences, Biotechnology, Molecular Biology +16