Concepedia

UV Spectrophotometric Method for Determination of the Dissolution Profile of Rivaroxaban

Mustafa Çelebi̇er, Mustafa Sinan Kaynak, Sacide Altınöz, Selma Şahin

Dissolution Technologies · 2014 · 17 citations · 7 references

DOIFull text

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Concepts

Abstract

Rivaroxaban is an oral anticoagulant that is the first available orally active direct Factor Xa inhibitor. In this study, a UV spectrophotometric method was developed for the determination of rivaroxaban content in pharmaceutical formulations and the amount of rivaroxaban released in tablet dissolution studies. The dissolution profile of rivaroxaban was successfully determined with the validated method.

References

7

Trends in quality in the analytical laboratory. II. Analytical method validation and quality assurance

Isabel Taverniers, Marc De Loose, Erik Van Bockstaele · TrAC Trends in Analytical Chemistry · 2004 · 925 citations

, , +16

Dissolution Testing for Generic Drugs: An FDA Perspective

Om Anand, Lawrence X. Yu, Dale P. Conner et al. · The AAPS Journal · 2011 · 270 citations · Full text

, , +14

Trends in quality in the analytical laboratory. I. Traceability and measurement uncertainty of analytical results

Isabel Taverniers, Marc De Loose, Erik Van Bockstaele · TrAC Trends in Analytical Chemistry · 2004 · 122 citations

, , +17

Comparison of UV spectrophotometric method and high performance liquid chromatography for the analysis of flunarizine and its application for the dissolution test

Kesarin Busaranon, Worapot Suntornsuk, Leena Suntornsuk · Journal of Pharmaceutical and Biomedical Analysis · 2005 · 23 citations

, , +13

Rapid and selective UV spectrophotometric and RP-HPLC methods for dissolution studies of oxybutynin immediate-release and controlled-release formulations

Manthena V. S. Varma, Aditya Mohan Kaushal, Sanjay Garg · Journal of Pharmaceutical and Biomedical Analysis · 2004 · 18 citations

, , +17