Experimental Biology and Medicine · 1959 · 187 citations · 0 references
Life SciencesBiochemistryNutritional SciencesHepatologyHuman NutritionSteroid BiochemistryBile Acid MetabolismBile FormationBile SecretionBiliary ExcretionLiver DiseaseSteroid ConjugationBile Acid Conjugation PathwaysBile Acid-conjugated MetabolitesConjugated Bile Acid MetabolismGlycine ConjugationResearch With Human SubjectsTaurine Conjugation
SummaryTaurine and glycine were given to human subjects and the bile acids studied. Taurine (0.5 g × 3 daily) markedly increased the proportion of taurine conjugated bile acids, whereas glycine (7 g × 3 daily) did not change the bile acid pattern of the normal subject. The findings have been discussed in relation to conjugation of bile acids under normal and pathological conditions.