Effect of Prolonged Ethanol Ingestion on the Transport and Metabolism of Lipids in Man

Abstract

ETHANOL ingestion is often associated with abnormalities in the transport and metabolism of lipids.1 Clinical manifestations of these abnormalities include triglyceride accumulation in the liver and in the serum. Zieve2 has called attention to the development of hyperlipemia associated with jaundice, reticulocytosis and deposition of fat in the liver in some alcoholic patients. However, it is evident that fatty infiltration of the liver may occur in such patients in the absence of hyperlipemia.3 Experimental observations in animals have suggested that the effects of ethanol on lipid metabolism may be independent of dietary factors.1,4,5 The present study demonstrates that . . .