Concepedia

Age-Related Changes in Fibromodulin and Lumican in Human Intervertebral Discs

Robert SZTROLOVICS, Mauro Alini, John S. Mort, Peter J. Roughley

Spine · 1999 · 120 citations · 30 references

DOI

Abstract

Growth, aging, and degeneration of the intervertebral disc are associated with changes in the abundance and structure of fibromodulin and lumican, which presumably influence the functional properties of the tissue.

References

30

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The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration.

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Preliminary Evaluation of a Scheme for Grading the Gross Morphology of the Human Intervertebral Disc

J. Paul Thompson, R. H. Pearce, Martin T. Schechter et al. · Spine · 1990 · 856 citations