Expression of ABC Transporters is an Unfavorable Prognostic Factor in Laryngeal Squamous Cell Carcinoma

Abstract

The results of this study revealed that the presence of ABCG2 and/or ABCB1 is predictive for malignant progression and is an independent prognostic factor in LSCC. The mechanism of ABC transporters may contribute to chemotherapy resistance by promoting proliferation and/or suppressing apoptosis.