New oxylipins produced at the end of a diatom bloom and their effects on copepod reproductive success and gene expression levels

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo Vandesompele, Katleen De Preter, Filip Pattyn et al. · Genome biology · 2002 · 20.1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +14

Relative expression software tool (REST(C)) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

Michael W. Pfaffl · Nucleic Acids Research · 2002 · 7.4K citations · Full text

Life Sciences, Biostatistics, Molecular Biology +15

Normalization of Real-Time Quantitative Reverse Transcription-PCR Data: A Model-Based Variance Estimation Approach to Identify Genes Suited for Normalization, Applied to Bladder and Colon Cancer Data Sets

Claus L. Andersen, Jens Ledet Jensen, Torben F. Ørntoft · Cancer Research · 2004 · 7.2K citations

Life Sciences, Biostatistics, Molecular Biology +17

Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper – Excel-based tool using pair-wise correlations

Michael W. Pfaffl, Aleš Tichopád, Christian Prgomet et al. · Biotechnology Letters · 2004 · 5.1K citations

Life Sciences, Genetics, Molecular Biology +12

The evolutionary and ecological role of heat shock proteins

Jesper Givskov Sørensen, Torsten Nygaard Kristensen, Volker Loeschcke · Ecology Letters · 2003 · 1.4K citations

Life Sciences, Biology, Evolutionary Biology +17