Concepedia

The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells

Fadi Gurgis, Yiu To Yeung, Minying Tang, Benjamin Heng, Michael E. Buckland, Alaina J. Ammit, Joonas Haapasalo, Hannu Haapasalo, Gilles J. Guillemin, Thomas Grewal,

Oncogene · 2014 · 71 citations · 31 references

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31

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature · 2008 · 7.8K citations · Full text

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The p38 MAP kinase pathway signals for cytokine‐induced mRNA stabilization via MAP kinase‐activated protein kinase 2 and an AU‐rich region‐targeted mechanism

Reinhard Winzen · The EMBO Journal · 1999 · 775 citations · Full text

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Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

Maria-del-Mar Inda, Rudy Bonavia, Akitake Mukasa et al. · Genes & Development · 2010 · 541 citations · Full text

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Expression of indoleamine 2,3‐dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons

Gilles J. Guillemin, George A. Smythe, Osamu Takikawa et al. · Glia · 2004 · 482 citations

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MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels

Armin Neininger, Dimitris L. Kontoyiannis, Alexey Kotlyarov et al. · Journal of Biological Chemistry · 2002 · 389 citations · Full text

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