Concepedia

5-Fluorouracil (5-FU) induced apoptosis in gastric cancer cell lines: role of the p53 gene

Mitsuhiko Osaki, Shigeru Tatebe, Akira Gotō, Hisae Hayashi, M Oshimura, Hisao Ito

APOPTOSIS · 1997 · 56 citations · 25 references

DOI

Concepts

References

25

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

Zoltán N. Oltval, Curt Milliman, Stanley J. Korsmeyer · Cell · 1993 · 6K citations

, , +12

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

J. Wade Harper · Cell · 1993 · 5.7K citations

, , +14

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

Toshiyuki Miyashita, John C. Reed · Cell · 1995 · 4.1K citations · Full text

, , +12

Participation of p53 protein in the cellular response to DNA damage.

Michael B. Kastan, Onyinye Onyekwere, D Sidransky et al. · PubMed · 1991 · 3.8K citations

, , +14

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

Elisheva Yonish-Rouach, Dalia Resnftzky, Joseph Lotem et al. · Nature · 1991 · 2.1K citations

, , +13