Induction of glutathione peroxidase by linoleic acid hydroperoxide in Hansenula mrakii.

Abstract

The yeast Hansenula mrakii IFO 0895 could grow in a minimal medium containing 4 mM linoleic acid hydroperoxide, and the hydroperoxide moiety of linoleic acid hydroperoxide was reduced to the alcohol moiety. The activity of glutathione peroxidase was detected from the insoluble fractions of the cell homogenates of H. mrakii IFO 0895 only when the cells were grown in a linoleic acid hydroperoxide-containing medium.