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"Crystalline" Virus-Like Particles from Skin Papillomas Characterized by Intranuclear Inclusion Bodies.
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1949
Year
Synthetic VirologyPathologyAnatomyDermatologyVirus StructurePathologic LesionElectron MicroscopySurgical PathologyVirus-like ParticlesSummaryvirus-like ParticlesCutaneous BiologyHistopathologySkin Papillomas CharacterizedVirologyTypical VerrucaeDermatopathologyIntranuclear Inclusion BodiesGeneral PathologyMedicine
SummaryVirus-like particles that tend to be arranged in a crystalline-like pattern have been observed by electron microscopy in as study of suspensions of 5 skin papillomas. Histological examination of the same tissues revealed intranuclear inclusion bodies and characteristic cytoplasmic masses in the cells of the hyperplastic epidermis. Thirty-one lesions with similar histological appearance were encountered along with 158 typical verrucae in a review of surgical pathological material.