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Analgetic Property of Vitamin K
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1955
Year
Pain MedicinePharmacotherapyVitamin KNutrient BioavailabilityBioanalysisAnalytical ChemistryPain ManagementConsiderable Thermoanalgetic EffectAnesthetic PharmacologyChromatographyHealth SciencesComplete Analgetic EffectEndocrinologyPharmacologyAnaesthetic AgentPain ResearchVitamin NutritionVitamin K AntagonistsPhysiologyThermoanalgetic EffectAnesthesiaMedicineAnesthesiology
Conclusion1. Vit. K has shown a considerable thermoanalgetic effect that is also evident in suprarenaletomised animals. This effect is stronger than the thermoanalgetic effect of morphine. 2. Vit. K has shown a strong sedative effect not being due to the mobilisation of the hormones of the suprarenal glands. 3. Vit. K has no depressive property on the cortical or subcortical motor-centers. 4. In patients with inoperative carcinomas and sarcomas with metastases and severe pains, vit. K showed such a pronounced analgetic property that we could cease administration of morphine and barbiturates. The complete analgetic effect was obtained in 73% of cases.