Generation of Nitrile Oxides from Oximes Using <i>t</i>-BuOI and Their Cycloaddition

Abstract

tert-Butyl hypoiodite (t-BuOI) was found to be a powerful reagent for the cycloaddition of oximes and alkenes/alkynes, leading to the formation of a variety of isoxazolines or isoxazoles under mild conditions.