Mechanical Delivery of Aerosolized Gadolinium-DTPA for Pulmonary Ventilation Assessment in MR Imaging

Abstract

The feasibility of applying Gd-DTPA as a contrast agent to demonstrate pulmonary ventilation in large animals has been described before. The results of this refined technique substantiate the potential of Gd-based ventilation MR imaging by improving aerosol distribution and shortening the nebulization duration in the healthy lung.