Formulation and evaluation of Antiwrinkle activity of Cream and Nano emulsion of Moringa oleifera seed oil

Abstract

Aging is a natural phenomenon that leads to various changes in the physiology of the skin. The changes occurring in the physiology of the skin makes the candidate to appear old. Application of antiaging creams is the best choice even though various treatment methods are available because it nourishes skin and prevents or repairs fine lines and wrinkles thus giving young looking appearance. Apart from that, nature has an excellent anti-aging remedies that acts externally whereas internally to delay aging signs and some will act to repair and prevent aging signs. In the present study, Moringa oleifera was studied for its antiaging benefits as the seed oil is rich in antioxidants that might prevent the oxidative damage of the skin. By using the Moringa seed oil in various ratios, cream and nano emulsion were prepared and they are characterised for its physical properties. The best formula was optimised which has been evaluated for antiaging activity using animal models by topical application of the formulations for two times a day upto 30days and the results were compared with the standard. The results showed that the nano emulsion formulation was found more efficacious than the cream formulation. This shows that the moringa oil has a good antiaging activity and donot showed any irritant effects on skin.