Concepedia

Depletion of Glutathione in Normal and Malignant Human Cells In Vivo by Buthionine Sulfoximine: Clinical and Biochemical Results

Peter J. O’Dwyer, Thomas C. Hamilton, Robert C. Young, Frank LaCreta, Ned Z. Carp, Kenneth D. Tew, Kristin Padavic, Robert L. Comis, Robert F. Ozols

JNCI Journal of the National Cancer Institute · 1992 · 100 citations · 0 references

DOI

Concepts

MedicineOncologyPharmacologyCancer PharmacologyMolecular OncologyNeoplasiaCancer MetabolismGlutathione ConjugationGlutathione MetabolismMalignant NeoplasmsGlutathione HomeostasisGlutathione Redox SystemGlutathione SystemIntracellular Glutathione PoolsReduced Glutathione

Abstract

P. J. O'Dwyer, T. C. Hamilton, R. C. Young, F. P. LaCreta, N. Carp, K. D. Tew, K. Padavic, R. L. Comis, R. F. Ozols; Depletion of Glutathione in Normal and