Journal of the American Chemical Society · 2014 · 90 citations · 32 references
Novel OrganocatalystsEngineeringHeterocyclicAlkene Metathesis3-Substituted CyclohexyneOrganic ChemistryNew Heterocyclic CompoundsOrganometallic CatalysisChemistryHeterocycle ChemistryBiomolecular EngineeringElusive Intermediate
We report the strategic use of cyclohexyne and the more elusive intermediate, cyclopentyne, as a tool for the synthesis of new heterocyclic compounds. Experimental and computational studies of a 3-substituted cyclohexyne are also described. The observed regioselectivities are explained by the distortion/interaction model.
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The use of arynes in organic synthesis
Hélène Pellissier, Maurice Santelli · Tetrahedron · 2003 · 537 citations