Effects of Liver Feeding on Growth and Ovarian Development in the Hyperthyroid Rat

Abstract

The administration of liver completely counteracted the retardation of growth and inhibition of ovarian development observed in immature rats fed toxic amounts of thyroid. Wheat germ, yeast, or increased amounts of salt mixture, casein, thiamine, riboflavin, pyridoxine, calcium pantothenate, nicotinic acid, inositol, p-aminobenzoic acid, biotin or folic acid were ineffective in this regard. The suggestion is made that liver contains some factor other than the above required for normal growth and ovarian development in the immature thyroid-fed rat.