PB-5266 A, B and C, new monobactams. I Taxonomy, fermentation and isolation.

Toshiyuki Kato, HIROSHI HINOO, JUN''ICHI SHOJI, Koichi Matsumoto, Tatsuo Tanimoto, TERUO HATTORI, KEIICHIRO HIROOKA, Eiji Kondo

The Journal of Antibiotics · 1987 · 22 citations · 7 references

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Abstract

New monobactams, PB-5266 A, B and C were isolated from the culture filtrate of Cytophaga johnsonae PB-5266 by various types of column chromatography and preparative reverse phase HPLC. PB-5266 A, B and C exhibited weak antibacterial activity against a sensitive mutant of Escherichia coli to beta-lactam antibiotics.

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