Improved post-transcriptional processing of an MDR1 retrovirus elevates expression of multidrug resistance in primary human hematopoietic cells

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species

Margaret A. Goodell, Michael Rosenzweig, Hyung L. Kim et al. · Nature Medicine · 1997 · 1.1K citations

Life Sciences, Cell Biology, Hematology +11

Construction and properties of retrovirus packaging cells based on gibbon ape leukemia virus

A. Dusty Miller, J. Victor Garcia, N von Suhr et al. · Journal of Virology · 1991 · 637 citations · Full text

Life Sciences, Biotechnology, Cell Biology +11

Selection of Drug-Resistant Bone Marrow Cells in Vivo After Retroviral Transfer of Human <i>MDR</i> 1

Brian P. Sorrentino, Stephen J. Brandt, David M. Bodine et al. · Science · 1992 · 494 citations

Medicine, Cancer Biology, Pharmacology +14

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells

Rafat Abonour, David A. Williams, Lawrence H. Einhorn et al. · Nature Medicine · 2000 · 277 citations

Life Sciences, Biotechnology, Genetics +13

Improved Gene Transfer Into Baboon Marrow Repopulating Cells Using Recombinant Human Fibronectin Fragment CH-296 in Combination With Interleukin-6, Stem Cell Factor, FLT-3 Ligand, and Megakaryocyte Growth and Development Factor

Hans‐Peter Kiem, Robert G. Andrews, Julia Morris et al. · Blood · 1998 · 254 citations

Pharmacy, Cell Biology, Hematology +17