Advances in Neonatal Care · 2013 · 16 citations · 24 references
MedicineChild HealthPediatricsNeonatal HealthNeonatologyNeurocritical CareHypoxic-ischemic EncephalopathyNeonatal Intensive CareNeonatal ResuscitationNeonatal TransportNewborn CarePediatric Neurocritical CareHypothermiaHypothermia In NeonatesHypothermia TreatmentNeonatal Hypoxic-ischemic EncephalopathyNeonatal Transport TeamOutreach RolesPerinatal Hypoxic-ischemic EncephalopathyStabilization
Hypoxic-ischemic encephalopathy (HIE) occurring during the perinatal period is one of the primary causes of severe, long-term neurological deficits in children. Initial systemic supportive therapy remains a critical aspect of HIE management. In addition to support therapy, the widespread use of hypothermia has demonstrated a reduction in death and neurodevelopmental disability in infants with moderate to severe HIE. Neonates with HIE born outside of tertiary care centers must be rapidly identified as hypothermia candidates and have emergent transport arranged. While waiting for the transport team to arrive, these neonates often require intensive stabilization, including meticulous temperature management. This article examines the need for HIE outreach teaching programs, assists in the identification of a neonate for hypothermia therapy, and supplies evidence-based recommendations for the initial stabilization and care of neonates delivered at nontertiary care facilities. The guidelines and materials supplied represent the outreach model used by our regional hypothermia center and disseminated to the surrounding referral hospitals.
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Whole-Body Hypothermia for Neonates with Hypoxic–Ischemic Encephalopathy
Seetha Shankaran, Abbot R. Laptook, Richard A. Ehrenkranz et al. · New England Journal of Medicine · 2005 · 2.8K citations · Full text
Medicine, Child Health, Pediatrics +14
Chorioamnionitis and Cerebral Palsy in Term and Near-Term Infants
Yvonne W. Wu · JAMA · 2003 · 603 citations
Neonatal cytokines and coagulation factors in children with cerebral palsy
Karin B. Nelson, James M. Dambrosia, Judith K. Grether et al. · Annals of Neurology · 1998 · 559 citations
Medicine, Immunology, Pediatrics +17