Molecular structural basis of ligand selectivity for 5-HT2 versus 5-HT1C cortical receptors

Multiple Serotonin Receptors: Differential Binding of [3H]5-Hydroxytryptamine, [3H]Lysergic Acid Diethylamide and [3H]Spiroperidol

Stephen J. Peroutka, Solomon H. Snyder · Molecular Pharmacology · 1979 · 1.4K citations

Medicine, Neuroscience, Pharmacology +15

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor

David Julius, Amy B. MacDermott, Richard Axel et al. · Science · 1988 · 695 citations

Life Sciences, Molecular Biology, Neuroscience +17

Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites

Georg Engel, M. G�thert, Daniël Hoyer et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1986 · 680 citations

Life Sciences, Neuroscience, Pharmacology +14

Serotonergic component of neuroleptic receptors

Josée E. Leysen, C. J. E. Niemegeers, J.P. Tollenaere et al. · Nature · 1978 · 626 citations

Life Sciences, Neuroscience, Pharmacology +14