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Effect of Ethylenediaminetetraacetate on Lipide Peroxide Formation and Succinoxidase Inactivation by Ultraviolet Light.

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1957

Year

Abstract

1. EDTA inhibits lipide peroxide formation in rat liver homogenates and in rat liver mitochondria exposed to ultraviolet irradiation. 2. Ultraviolet light inhibits succinoxidase in mitochondria and EDTA protects it from inactivation. The protection is proportional to the inhibition of lipide peroxide formation. 3. EDTA does not inhibit lipide peroxide formation in pure methyl linolenate emulsions irradiated with ultraviolet light but does inhibit both the antioxidant effect of ascorbic acid and the iron catalysis of peroxide formation in these emulsions.