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Synthesis of O2'-Methyluridine, O2'-Methylcytidine, N4,O2'-Dimethylcytidine and N4,N4,O2'-Trimethylcytidine from a Common Intermediate.

A. Nyilas, J. Chattopadhyaya, Alexander F. Drake, B. Öberg, J. Chattopadhyaya

Acta chemica Scandinavica/Acta chemica Scandinavica. B, Organic chemistry and biochemistry/Acta chemica Scandinavica. A, Physical and inorganic chemistry/Acta chemica Scandinavica. Series B. Organic chemistry and biochemistry/Acta chemica Scandinavica. Series A, Physical and inorganic chemistry · 1986 · 31 citations · 0 references

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Abstract

A facile synthesis of the title compounds from a readily accessible precursor, 3',5'-O-bis-protected O4-(2-nitrophenyl)uridine, is described.