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Isolation of a Feline Virus Associated with Intranuclear Inclusion Bodies
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1958
Year
Tissue Culture FluidViral PathogenesisImmunologyPathologyIntranuclear InclusionsVirus StructureFeline Virus AssociatedDiagnostic VirologyXenotransplantationVeterinary PathologySmall Animal Internal MedicineVirologyTissue Culture PreparationsMolecular VirologyPathogenesisVeterinary ScienceVirus-host InteractionMedicineAnimal Virus
Summary1) A viral agent cytopathogenic for feline kidney tissue culture was isolated from a cat with a respiratory infection. It has been shown to be capable of reproducing the illness in susceptible kittens with the development of specific neutralizing antibodies. Intranuclear inclusions have been demonstrated in both tissue culture preparations and kittens in which the disease was reproduced. 2) The agent has survived lyophilization and storage in tissue culture fluid for at least 3 months at —60°C.