Concepedia

<i>Interleukin 28B</i> rs12979860 Single‐Nucleotide Polymorphism Predicts Spontaneous Clearance of Hepatitis C Virus in Children

Giuseppe Indolfi, Giusi Mangone, Pier Luigi Calvo, Elisa Bartolini, Marta Regoli, Daniele Serranti, Carmelina Calitri, Pier‐Angelo Tovo, Maurizio de Martino, Chiara Azzari,

Journal of Pediatric Gastroenterology and Nutrition · 2013 · 33 citations · 18 references

DOI

Abstract

The present study showed that, as already demonstrated in adults, children with the rs12979860 C/C SNP of the interleukin 28B gene have a higher probability of spontaneous clearance of hepatitis C virus.

References

18

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Dongliang Ge, Jacques Fellay, Alexander Thompson et al. · Nature · 2009 · 3.5K citations · Full text

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

David L. Thomas, Chloe L. Thio, Maureen P. Martin et al. · Nature · 2009 · 2.1K citations

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IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

Nature Genetics · 2009 · 1.8K citations

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Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

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