Experimental Eosinophilia V. Specificity of Regional Lymph Node Responses to Antigen-Antibody Systems.

Abstract

Eosinophilic granular cell infiltrations into sinuses of regional popliteal lymph nodes of the rabbit were demonstrated. These followed reversed passive sensitization experiments at foot pad sites in response to antigen-antibody union. Systems of varying character found effective were: bovine serum albumin and bovine serum gamma globulin with respective corresponding antisera of rabbit, guinea pig, and chicken origins; diphtheria toxoid with corresponding rabbit, guinea pig, and horse antitoxin; and tetanus toxoid-horse antitoxin.