Retroinfusion of NFκB decoy oligonucleotide extends cardioprotection achieved by CD18 inhibition in a preclinical study of myocardial ischemia and retroinfusion in pigs

Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

Jian-Guo Geng, Michael P. Bevilacquat, Kevin L. Moore et al. · Nature · 1990 · 976 citations

Life Sciences, Cell Biology, Immunology +12

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction

Anique Ducharme, Stefan Frantz, Masanori Aikawa et al. · Journal of Clinical Investigation · 2000 · 808 citations · Full text

Medicine, Cardiology, Pathobiology +12

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

Stéphane Heymans, Aernout Luttun, Dieter Nuyens et al. · Nature Medicine · 1999 · 797 citations

Medicine, Cardiology, Pharmacology +14

Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion.

Paul J. Simpson, Robert F. Todd, Joseph C. Fantone et al. · Journal of Clinical Investigation · 1988 · 641 citations · Full text

Medicine, Cardiology, Immunology +17

In vivo transfection of cis element “decoy” against nuclear factor- κB binding site prevents myocardial infarction

Ryuichi Morishita, Toshiko Sugimoto, Motokuni Aoki et al. · Nature Medicine · 1997 · 589 citations

Life Sciences, Cardiology, Molecular Biology +13