IFN-β induces serine phosphorylation of Stat-1 in Ewing's sarcoma cells and mediates apoptosis via induction of IRF-1 and activation of caspase-7

Principles and Practice of Pediatric Oncology

Annals of Internal Medicine · 1990 · 2K citations

Medicine, Oncology, Pediatrics +12

Maximal activation of transcription by statl and stat3 requires both tyrosine and serine phosphorylation

Zilong Wen, Zhong Zhong, James Darnell · Cell · 1995 · 2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Interferon beta‐1b is effective in relapsing‐remitting multiple sclerosis

D. W. Paty, D.K.B. Li · Neurology · 1993 · 2K citations · Full text

Pharmacy, Neurology, Pharmacotherapy +14

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Olivier Delattre, Jessica Zucman‐Rossi, Béatrice Plougastel-Douglas et al. · Nature · 1992 · 1.9K citations

Life Sciences, Genetics, Molecular Genetics +17

Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

Marco Antonio Meraz‐Ríos, J. Michael White, Kathleen C. F. Sheehan et al. · Cell · 1996 · 1.7K citations · Full text

Life Sciences, Genetics, Molecular Biology +9