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1,6-Dihydro-3(2H)-pyridinones as synthetic intermediates. A convenient total synthesis of (.+-.)-cleavamine.
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1981
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EngineeringEthyl 1Natural SciencesDiversity-oriented SynthesisOrganic ChemistryChemistryHeterocycle ChemistrySynthesis MethodPharmacologySynthetic ChemistryConvenient Total SynthesisBiomolecular EngineeringNatural Product Synthesis
A novel and convenient total synthesis of (±)-cleavamine (1) starting from ethyl 1, 6-dihydro-3 (2H)-pyridinone-1-carboxylate (2) is described.