The Journal of Antibiotics · 1983 · 17 citations · 0 references
MedicineMedicinal ChemistryPharmacologyCancer PharmacologyChemotherapySynthetic Medicinal ChemistryAntitumor AntibioticsCytotoxic ChemotherapyMetabolism Of Anticancer AgentsPharmacodynamics Of Anticancer AgentsPharmacodynamics Of Anticancer DrugsPharmacokinetics Of Anticancer DrugsAntibiotic Discovery
The syntheses and antitumor activity of tomaymycin analogs are described. Structural modification of such parts of tomaymycin as the ethylidenepyrrole ring, animal bond, and substituents of the benzene ring are discussed.