Cornea · 2014 · 16 citations · 12 references
MedicineOphthalmologySurgeryOcular AnatomyOcular DiseaseOphthalmic SurgeryConjunctival DisordersConjunctival PathologyConjunctival SurgeryAmniotic Membrane TherapyBulbar ConjunctivaConjunctival ClosureConjunctival SuturingFunctional Outcomes After SurgeryLubricationSymblepharon FormationTopical Steroid Therapy
PURPOSE: The aim of this study was to describe a novel surgical method for the sutureless placement of amniotic membrane on the bulbar and palpebral conjunctiva in the setting of ocular-involving acute Stevens-Johnson syndrome. METHODS: Within 6 days of an acute Stevens-Johnson episode, a 27-year-old male developed early symblepharon, despite aggressive lubrication and topical steroid therapy. He underwent symblepharon lysis and placement of an amniotic membrane wrapped around a symblepharon ring. RESULTS: The patient maintained 20/20 vision in each eye with no recurrent symblepharon formation except for the temporal canthus (which was not covered with amniotic membrane). CONCLUSIONS: Symblepharon rings covered in amniotic membrane provide a sutureless way to fixate amniotic membrane to the bulbar and palpebral conjunctiva. This gave very good anatomic and functional outcomes in a patient with acute Stevens-Johnson syndrome. Future research could be directed toward the development of a symblepharon ring that will be able to better protect the far temporal conjunctiva.
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Amniotic membrane in the surgical management of acute toxic epidermal necrolysis
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