STAT3 Regulation by S-Nitrosylation: Implication for Inflammatory Disease

Jinsu Kim, Je‐Seong Won, Avtar Singh, Anand K. Sharma, Inderjit Singh

Antioxidants and Redox Signaling · 2013 · 94 citations · 38 references

Abstract

Our results indicate the regulation of STAT3 by NO-based post-translational modification (S-nitrosylation). These findings have important implications for the development of new therapeutics targeting STAT3 for treating diseases associated with inflammatory/immune responses and abnormal cell proliferation, including cancer.

References

38