Publication | Closed Access
No association between the XPD (Lys751G1n) polymorphism or the XRCC3 (Thr241Met) polymorphism and lung cancer risk.
132
Citations
5
References
2001
Year
Dna DamageGeneticsGenetic EpidemiologyHuman PolymorphismPathologyMolecular BiologyLung Cancer RiskPublic HealthMolecular DiagnosticsSmoking Related Lung DiseaseCancer ResearchGenome InstabilityDna Repair CapacityDna Repair ProteinsCancer GeneticsLung CancerEpidemiologyCancer RiskCancer EpidemiologyMedicineMutagenesis
DNA repair helps to protect the genome from tobacco-induced damage. Reduced DNA repair capacity may predispose individuals to lung cancer [(1)][1] . Polymorphisms in genes encoding DNA repair proteins may modulate susceptibility to tobacco lung carcinogens. Bulky DNA adducts induced by chemical
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