A new macrocyclic lactam antibiotic, BE-14106. I. Taxonomy, isolation, biological activity and structural elucidation.

KATSUHISA KOJIRI, Shigeru Nakajima, Hajime Suzuki, Hisao Kondo, Hiroyuki Suda

The Journal of Antibiotics · 1992 · 47 citations · 13 references

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Abstract

A Streptomyces strain labeled A14106 was isolated and found to produce a novel 20-membered macrocyclic lactam derivative, BE-14106, which exhibited both cytotoxic activity against murine tumor cell lines and antimicrobial activity.

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