Effect of Adrenalectomy on Wound Healing in Normal and in Stressed Rats.

Abstract

1. The bursting pressures of healing laparotomy wounds, made 15 days after bilateral adrenalectomy were equal to or superior to those of normal control rats. 2. In adrenalectomized rats, maintained on a small fixed dosage of aqueous adrenal cortex extract, skin-excision-stress did not result in depression of the bursting pressure of 5th day laparotomy wounds, as is the case with non-adrenalectomized rats subjected to the same stress.