Highly Convergent Synthesis of Chiral Bicyclophosphinates by Domino Hydrophosphinylation/Michael/Michael Reaction

Pierre Fourgeaud, Bénédicte Daydé-Cazals, Jean‐Noël Volle, Jean‐Pierre Vors, Arie van der Lee, Jean‐Luc Pirat, David Virieux

Organic Letters · 2011 · 15 citations · 29 references

Concepts

Abstract

Diastereoselective domino reactions of iminoalcohols and allenyl H-phosphinates produce chiral phosphorus bicycles in a regio- and stereoselective fashion. A predictive model for diastereoselection is used for these new chiral phosphinic esters.

References

29