International Journal of Stroke · 2015 · 31 citations · 14 references
When considered together as radiological expressions of small vessel disease, presence and severity of severe leukoaraiosis and lacunes on baseline computer tomography scan are associated with poor clinical outcomes in patients treated with i.v. thrombolysis.
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Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden
Julie Staals, Stephen Makin, Fergus Doubal et al. · Neurology · 2014 · 967 citations · Full text
Severity of leukoaraiosis correlates with clinical outcome after ischemic stroke
Ethem Murat Arsava, Rosanna Rahman, Jonathan Rosand et al. · Neurology · 2009 · 207 citations · Full text