Advanced Materials · 2016 · 64 citations · 39 references
EngineeringBioengineeringBiological EngineeringBiomaterialsMorphogenesisTissue EngineeringBiomaterials For Tissue EngineeringCell-scaffold InteractionsExtracellular MatrixHydrogelsTissue ArchitectureTissue MorphogenesisExtracellular Matrix MimicryExtracellular Matrix ProductionExtracellular Matrix ScaffoldsHigh-content ScreeningMicroscale Tissue EngineeringScaffold-free Tissue AssemblyScaffold-free Tissue EngineeringTissue Engineering Scaffold Fabrication
Material-free tissues are assembled using solely cells. Microstructured hydrogel templates and high content screening allow the formation of centimeter-scale tissues with precise architectures. Similar to developing tissues, these contract autonomously, controllably shift shape, self-scaffold by secreting extracellular matrix, and undergo morphogenesis. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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