Simvastatin inhibits the expression of inflammatory cytokines and cell adhesion molecules induced by <scp>LPS</scp> in human dental pulp cells

Abstract

Simvastatin has a suppressing effect on LPS-induced inflammatory cytokine, cell adhesion molecules and NF-κB transcription factors in HDPCs. Therefore, simvastatin might be a useful candidate as a pulp-capping agent in vital pulp therapy.