Simvastatin Promotes Osteoblast Differentiation and Mineralization in MC3T3-E1 Cells

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

Hans-Peter Gerber, Thiennu H. Vu, Anne Ryan et al. · Nature Medicine · 1999 · 2.1K citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +13

Stimulation of Bone Formation in Vitro and in Rodents by Statins

Gregory R. Mundy, R.J. Burriss Garrett, S. E. Harris et al. · Science · 1999 · 1.8K citations

Medicine, Pharmacology, Pharmacotherapy +16

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals.

Yasuko Kureishi, Zhengyu Luo, Ichiro Shiojima et al. · Nature Medicine · 2000 · 1.4K citations

Life Sciences, Biochemistry, Pharmacology +12

Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats

C. Maniatopoulos, Jaro Sodek, A. H. Melcher · Cell and Tissue Research · 1988 · 1.3K citations

Medicine, Cell Biology, Developmental Biology +16

Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability

Brian P. Eliceiri, Robert Paul, Pamela L. Schwartzberg et al. · Molecular Cell · 1999 · 817 citations · Full text

Medicine, Cancer Biology, Oncology +17